Description

Boc-(R)-2-Aminomethy-Pentanoic Acid CAS NO 941292-79-1 is a high-purity, non-natural amino acid derivative featuring a tert-butoxycarbonyl (Boc) protecting group on the amine functionality. This compound is a critical chiral building block for the synthesis of complex peptides and peptidomimetics, enabling precise control over stereochemistry and molecular architecture. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, medicinal chemistry, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediates: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease research.
• Peptide Synthesis: Serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS) for creating custom peptides with specific sequences and properties.
• Medicinal Chemistry & Drug Discovery: Used in structure-activity relationship (SAR) studies and lead optimization to explore novel chemical spaces and improve drug candidate profiles.
• Bioconjugation & Probe Development: Facilitates the site-specific modification of peptides and proteins for creating diagnostic probes, imaging agents, and antibody-drug conjugates (ADCs).
• Academic & Industrial Research: Employed in biochemical and pharmacological research to study enzyme mechanisms, receptor-ligand interactions, and cellular signaling pathways.

Basic Information

Item	Detail
Product Name	Boc-(R)-2-Aminomethy-Pentanoic Acid
CAS No.	941292-79-1
Molecular Formula	C11H21NO4
Molecular Weight	231.29 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)pentanoic Acid; (R)-2-(Boc-amino)pentanoic Acid; Boc-D-Norvaline-OH; Boc-D-Nva-OH; (R)-N-Boc-norvaline; N-(tert-Butoxycarbonyl)-D-norvaline; Nα-Boc-D-norvaline; D-Norvaline, N-Boc-
EINECS	Contact for details

Quality Control

Our Boc-(R)-2-Aminomethy-Pentanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.