Description

(2R,3S)-3-(3-Bromophenyl)-4-(4-Chlorophenyl)Butan-2-Ol is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. Its defined stereochemistry and halogenated aromatic structure make it a critical precursor in the synthesis of advanced active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical and agrochemical sectors seeking to develop novel, stereospecific compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used as a building block for developing advanced, stereoselective pesticides and herbicides with enhanced efficacy and environmental profiles.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in academic and industrial research focused on developing new chiral catalysts and synthetic methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals requiring specific stereochemical configurations.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling in related pharmaceutical processes.

Basic Information

Product Name	(2R,3S)-3-(3-Bromophenyl)-4-(4-Chlorophenyl)Butan-2-Ol
CAS No.	941280-52-0
Molecular Formula	C16H16BrClO
Molecular Weight	339.66 g/mol
Synonyms	(2R,3S)-3-(3-Bromophenyl)-4-(4-chlorophenyl)butan-2-ol; 3-(3-Bromophenyl)-4-(4-chlorophenyl)butan-2-ol (2R,3S)-; (2R,3S)-3-(3-Bromophenyl)-4-(p-chlorophenyl)butan-2-ol; 941280-52-0; (2R,3S)-rel-3-(3-Bromophenyl)-4-(4-chlorophenyl)-2-butanol; Butan-2-ol, 3-(3-bromophenyl)-4-(4-chlorophenyl)-, (2R,3S)-
EINECS	Contact for details

Quality Control

Our (2R,3S)-3-(3-Bromophenyl)-4-(4-Chlorophenyl)Butan-2-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high stereochemical and chemical purity suitable for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, assay, chiral purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.