Description

(S)-1-(tert-Butoxycarbonyl)Piperidin-3-Yl Methanesulfonate is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its value lies in its role as a key synthon for introducing a functionalized piperidine moiety with defined stereochemistry into complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those working on active pharmaceutical ingredients (APIs), drug candidates, and other fine chemicals requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• API Synthesis: Used in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) that contain a substituted piperidine scaffold.
• Agrochemical Research: Serves as a precursor in the development of advanced pesticides and herbicides with specific stereochemical requirements.
• Asymmetric Synthesis: Employed in stereoselective reactions to construct complex molecular architectures for medicinal chemistry.
• Chemical Biology Probes: Utilized in the creation of labeled compounds and probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis organizations (CSOs) and CDMOs producing bespoke compounds for clients.

Basic Information

Product Name	(S)-1-(tert-Butoxycarbonyl)Piperidin-3-Yl Methanesulfonate
CAS No.	940890-90-4
Molecular Formula	C12H23NO5S
Molecular Weight	293.38 g/mol
Synonyms	(S)-3-(Methanesulfonyloxy)-1-Boc-piperidine; (S)-1-Boc-3-piperidyl methanesulfonate; (S)-1-(tert-Butoxycarbonyl)-3-piperidinol methanesulfonate; (S)-N-Boc-3-Hydroxypiperidine Methanesulfonate; (3S)-1-[(2-Methylpropan-2-yl)oxycarbonyl]piperidin-3-yl methanesulfonate; tert-Butyl (3S)-3-[(methylsulfonyl)oxy]piperidine-1-carboxylate; (S)-1-Boc-3-piperidinol mesylate; BOC-Piperidin-3-ol Mesylate (S-isomer)
EINECS	Contact for details

Quality Control

Our (S)-1-(tert-Butoxycarbonyl)Piperidin-3-Yl Methanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.