Description

1-Boc-3-[(3,4-Dichlorophenyl)Amino]-Pyrrolidine is a high-purity, advanced pharmaceutical intermediate featuring a protected pyrrolidine scaffold with a dichlorophenylamino substituent. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Protease Inhibitor Development: Serves as a core structure in the design and synthesis of protease enzyme inhibitors.
• Kinase Inhibitor Synthesis: Employed in the construction of novel kinase inhibitor libraries for high-throughput screening.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological targets and mechanisms of action.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects and scale-up under cGMP conditions for clinical trial material production.

Basic Information

Product Name	1-Boc-3-[(3,4-Dichlorophenyl)Amino]-Pyrrolidine
CAS No.	940865-87-2
Molecular Formula	C15H20Cl2N2O2
Molecular Weight	331.24 g/mol
Synonyms	tert-Butyl 3-[(3,4-dichlorophenyl)amino]pyrrolidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-[(3,4-dichlorophenyl)amino]pyrrolidine; N-Boc-3-(3,4-dichloroanilino)pyrrolidine; 3-[(3,4-Dichlorophenyl)amino]-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester; 1-Boc-3-(3,4-dichloroanilino)pyrrolidine; 940865-87-2; Boc-3-(3,4-dichloroanilino)pyrrolidine
EINECS	Contact for details

Quality Control

Our 1-Boc-3-[(3,4-Dichlorophenyl)Amino]-Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.