Description

3-(6-Chloro-Pyridazin-3-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate with a molecular formula of C14H20ClN3O3 and a molecular weight of 313.78. This compound is critical for research and development in medicinal chemistry, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) targeting neurological and cardiovascular pathways. It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers requiring a reliable, high-quality building block for complex organic synthesis.

Application

This high-purity intermediate serves as a versatile chemical scaffold in several advanced research and industrial applications:

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the pyridazine moiety for biological activity.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes to develop compounds with improved efficacy and safety profiles.
• Chemical Biology: Acts as a precursor for designing molecular probes and enzyme inhibitors to study biological pathways.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant scale for potential commercial manufacturing.

Basic Information

Product Name	3-(6-Chloro-Pyridazin-3-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	939986-59-1
Molecular Formula	C14H20ClN3O3
Molecular Weight	313.78 g/mol
Synonyms	tert-Butyl 3-[(6-chloropyridazin-3-yl)oxy]piperidine-1-carboxylate; 1-Boc-3-(6-chloro-3-pyridazinyloxy)piperidine; 3-(6-Chloro-3-pyridazinyloxy)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-3-(6-chloropyridazin-3-yloxy)piperidine; 3-(6-Chloro-pyridazin-3-yloxy)-piperidine-1-carboxylic acid tert-butyl ester; 939986-59-1; Boc-3-(6-chloro-pyridazin-3-yloxy)-piperidine
EINECS	Contact for details

Quality Control

Our 3-(6-Chloro-Pyridazin-3-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the specified 98+% purity and is free from critical impurities. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results from HPLC, NMR, and mass spectrometry analyses. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability and purity. Keep the container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.