Description

6-Bromo-2,3,4,5-Tetrahydro-1H-Benzo[B]Azepine is a high-value brominated heterocyclic building block, essential for advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, where its unique benzo-fused azepine structure enables complex molecular transformations. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of central nervous system (CNS) active compounds, potential antidepressants, and neurokinin receptor antagonists.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its bromine atom for further functionalization.
• Material Science: Serves as a building block for organic electronic materials and advanced polymers due to its rigid, fused-ring structure.
• Chemical Biology: Employed as a molecular probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Catalyst Ligand Synthesis: Potential precursor for creating novel chiral ligands used in asymmetric catalysis.
• Academic & Contract Research: Fundamental reagent for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6-Bromo-2,3,4,5-Tetrahydro-1H-Benzo[B]Azepine
CAS No.	939759-12-3
Molecular Formula	C10H12BrN
Molecular Weight	226.11 g/mol
Synonyms	6-Bromo-2,3,4,5-tetrahydro-1H-1-benzazepine; 1H-1-Benzazepine, 6-bromo-2,3,4,5-tetrahydro-; 6-Bromo-1,2,3,4,5,6-hexahydro-1-benzazepine; 6-Bromotetrahydro-1H-1-benzazepine; Benzoazepine, 6-bromo-2,3,4,5-tetrahydro-1H-; 6-Bromo-2,3,4,5-tetrahydrobenzo[b]azepine
EINECS	Contact for details

Quality Control

Our 6-Bromo-2,3,4,5-Tetrahydro-1H-Benzo[B]Azepine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.