Description

Ethyl 7-Methyl-5-Oxo-4,5-Dihydropyrazolo[1,5-A]Pyrimidine-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and serves as a key building block in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting kinase inhibition and other enzymatic pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for the design and development of new chemical entities (NCEs) in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of final APIs, especially in the production of specialized or orphan drugs.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for studying biological mechanisms and structure-activity relationships (SAR).
• Fine Chemical Manufacturing: An important building block for producing high-value, complex organic molecules in contract manufacturing organizations (CMOs).

Basic Information

Product Name	Ethyl 7-Methyl-5-Oxo-4,5-Dihydropyrazolo[1,5-A]Pyrimidine-2-Carboxylate
CAS No.	938022-20-9
Molecular Formula	C10H11N3O3
Molecular Weight	221.21 g/mol
Synonyms	Ethyl 7-methyl-5-oxo-4,5-dihydro-1H-pyrazolo[1,5-a]pyrimidine-2-carboxylate; 7-Methyl-5-oxo-4,5-dihydro-1H-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid ethyl ester; 1H-Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 4,5-dihydro-7-methyl-5-oxo-, ethyl ester; Ethyl 7-methyl-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidine-2-carboxylate; Pyrazolo[1,5-a]pyrimidine-2-carboxylate derivative; CAS 938022-20-9.
EINECS	Contact for details

Quality Control

Our Ethyl 7-Methyl-5-Oxo-4,5-Dihydropyrazolo[1,5-A]Pyrimidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.