Description

4-(4-Amino-Phenyl)-Tetrahydro-Pyran-4-Carboxylic Acid is a high-purity, multifunctional organic building block featuring both an aromatic amine and a carboxylic acid functional group on a tetrahydropyran scaffold. This unique structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small-molecule drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer and Material Science: Functional monomer for producing specialty polymers with tailored thermal or mechanical properties.
• Chemical Biology Research: Employed as a scaffold for developing molecular probes and bio-conjugation reagents.
• Advanced Organic Synthesis: Versatile starting material for constructing complex heterocyclic compounds and natural product analogs.

Basic Information

Product Name	4-(4-Amino-Phenyl)-Tetrahydro-Pyran-4-Carboxylic Acid
CAS No.	937651-78-0
Molecular Formula	C13H17NO3
Molecular Weight	235.28 g/mol
Synonyms	4-(4-Aminophenyl)tetrahydro-2H-pyran-4-carboxylic acid; 4-(4-Aminophenyl)-4-piperidinecarboxylic Acid (related structural analog); 4-Carboxy-4-(4-aminophenyl)tetrahydropyran; 4-Amino-α-(tetrahydro-2H-pyran-4-yl)benzenepropanoic acid (tautomer); ATTPC; 4-(p-Aminophenyl)tetrahydropyran-4-carboxylic acid; 4-(4-Aminophenyl)-4-piperidinecarboxylic acid derivative; 937651-78-0
EINECS	Contact for details

Quality Control

Our 4-(4-Amino-Phenyl)-Tetrahydro-Pyran-4-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.