Description

trans-3-Methyl-4-Aminotetrahydropyran CAS NO 937364-67-5 is a high-purity, chiral tetrahydropyran derivative featuring a strategically positioned amino group. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, valued for its ability to impart specific stereochemistry and functionality to target molecules. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used as a building block for developing advanced pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Employed in the synthesis of chiral ligands and organocatalysts for asymmetric synthesis applications.
• Fine Chemical Production: Serves as a precursor for various specialty and performance chemicals requiring a defined stereochemical center.
• Academic and Industrial Research: Utilized in chemical research for method development and exploring new synthetic pathways.

Basic Information

Product Name	trans-3-Methyl-4-Aminotetrahydropyran
CAS No.	937364-67-5
Molecular Formula	C6H13NO
Molecular Weight	115.17 g/mol
Synonyms	trans-4-Amino-3-methyltetrahydropyran; (3R,4S)-3-Methyl-4-aminotetrahydropyran; (3S,4R)-3-Methyl-4-aminotetrahydropyran; 4-Amino-3-methyltetrahydro-2H-pyran; 3-Methyl-4-aminotetrahydropyran; 3-Methyltetrahydro-4H-pyran-4-amine; 937364-67-5
EINECS	Contact for details

Quality Control

Our trans-3-Methyl-4-Aminotetrahydropyran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.