Description

1-(2,3-Dihydrobenzofuran-5-Yl)Cyclopropanecarboxylic Acid is a high-purity, synthetically versatile organic compound featuring a fused dihydrobenzofuran and cyclopropane carboxylic acid structure. This molecular architecture makes it a valuable and sophisticated building block for pharmaceutical research and fine chemical synthesis. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for creating novel active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the design and production of advanced crop protection agents and pesticides, leveraging its unique bicyclic scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials and novel polymers due to its rigid, fused-ring system.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP conditions.
• Academic & Industrial R&D: Utilized in exploratory chemistry for method development and creating compound libraries for biological screening.

Basic Information

Product Name	1-(2,3-Dihydrobenzofuran-5-Yl)Cyclopropanecarboxylic Acid
CAS No.	936727-45-6
Molecular Formula	C12H12O3
Molecular Weight	204.22 g/mol
Synonyms	5-(1-Carboxycyclopropyl)-2,3-dihydrobenzofuran; 1-(2,3-Dihydro-5-benzofuranyl)cyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 1-(2,3-dihydro-5-benzofuranyl)-; 1-(5-(2,3-Dihydrobenzofuranyl))cyclopropanecarboxylic Acid; 1-(2,3-Dihydrobenzofuran-5-yl)cyclopropane-1-carboxylic acid; 936727-45-6; DHBF-CPA
EINECS	Contact for details

Quality Control

Every batch of 1-(2,3-Dihydrobenzofuran-5-Yl)Cyclopropanecarboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and mass spectrometry, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.