Description

(S)-o-[2-(2-Phenyl-[1,3]Dioxan-4-Yl)-Ethyl]-Hydroxylamine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. Its value lies in its role as a key precursor for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in asymmetric synthesis and novel drug discovery.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used as a building block in stereoselective chemical reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Process Chemistry Development: Serves as a starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals requiring high enantiomeric purity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis.

Basic Information

Product Name	(S)-o-[2-(2-Phenyl-[1,3]Dioxan-4-Yl)-Ethyl]-Hydroxylamine Hydrochloride
CAS No.	936232-99-4
Molecular Formula	C₁₃H₁₉NO₃·HCl
Molecular Weight	273.75 g/mol (Free base: 237.29 g/mol)
Synonyms	(S)-2-[2-(2-Phenyl-1,3-dioxan-4-yl)ethyl]hydroxylamine hydrochloride; (S)-O-[2-(2-Phenyl-1,3-dioxan-4-yl)ethyl]hydroxylamine HCl; (S)-4-[2-(Aminooxy)ethyl]-2-phenyl-1,3-dioxane hydrochloride; (S)-2-Phenyl-4-[2-(aminooxy)ethyl]-1,3-dioxane hydrochloride; (S)-Hydroxylamine, O-[2-(2-phenyl-1,3-dioxan-4-yl)ethyl]-, hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-o-[2-(2-Phenyl-[1,3]Dioxan-4-Yl)-Ethyl]-Hydroxylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.