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Propionyl 3,4,6-Tri-o-Acetyl-2-Acetamido-2-Deoxy--D-Thiogalactopyranoside CAS NO 936026-72-1


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CAS No.:936026-72-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Propionyl 3,4,6-Tri-o-Acetyl-2-Acetamido-2-Deoxy--D-Thiogalactopyranoside is a sophisticated, high-purity thioglycoside building block essential for advanced synthetic chemistry. This compound is critical for researchers and manufacturers requiring precise glycosylation control in the development of novel bioactive molecules. It is primarily utilized in pharmaceutical R&D for the synthesis of complex glycoconjugates, carbohydrate-based drugs, and diagnostic probes.

Application

  • Pharmaceutical Intermediate: A key synthon for the synthesis of novel glycopeptide antibiotics, anti-cancer agents, and other therapeutic glycoconjugates.
  • Glycobiology Research: Used as a donor substrate in enzymatic and chemical glycosylation studies to investigate carbohydrate-protein interactions.
  • Diagnostic Probe Development: Serves as a precursor for labeling agents and molecular probes used in imaging and detection assays.
  • Carbohydrate Chemistry: An essential building block for the stereoselective construction of complex oligosaccharides and glycomimetics.
  • Bioconjugation: Facilitates the site-specific attachment of carbohydrate motifs to proteins, peptides, or surfaces for vaccine and drug delivery system development.

Basic Information

Product Name Propionyl 3,4,6-Tri-o-Acetyl-2-Acetamido-2-Deoxy--D-Thiogalactopyranoside
CAS No. 936026-72-1
Molecular Formula C₁₇H₂₅NO₉S
Molecular Weight 419.45 g/mol
Synonyms 2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-galactopyranosyl Propyl Disulfide (related); 1-Propionyl-3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-1-thio-β-D-galactopyranose; 2-Acetamido-1-S-propionyl-2-deoxy-3,4,6-tri-O-acetyl-1-thio-β-D-galactopyranose; β-D-Galactopyranose, 2-(acetylamino)-1,3,4,6-tetra-O-acetyl-2-deoxy-1-thio-, 1-propanoate; Thiogalactoside building block; Acetylated GalNAc thioglycoside donor.
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Quality Control

Our Propionyl 3,4,6-Tri-o-Acetyl-2-Acetamido-2-Deoxy--D-Thiogalactopyranoside is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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