Description

1H-Pyrazole-3-Carboxylic Acid, 4-(Trifluoromethyl)-, Ethyl Ester is a high-value fluorinated pyrazole derivative that serves as a critical building block in advanced organic synthesis. Its core value lies in the unique reactivity and physicochemical properties imparted by the trifluoromethyl-substituted pyrazole core, which is highly sought after for designing molecules with enhanced metabolic stability and lipophilicity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-inflammatory drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for creating chemical probes and tool compounds to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	1H-Pyrazole-3-Carboxylic Acid, 4-(Trifluoromethyl)-, Ethyl Ester
CAS No.	934758-94-8
Molecular Formula	C7H7F3N2O2
Molecular Weight	208.14 g/mol
Synonyms	Ethyl 4-(Trifluoromethyl)-1H-pyrazole-3-carboxylate; 4-(Trifluoromethyl)-1H-pyrazole-3-carboxylic Acid Ethyl Ester; 1H-Pyrazole-3-carboxylic acid, 4-(trifluoromethyl)-, ethyl ester; Ethyl 4-(trifluoromethyl)pyrazole-3-carboxylate; 4-Trifluoromethyl-1H-pyrazole-3-carboxylic acid ethyl ester; 934758-94-8; 4-(Trifluoromethyl)pyrazole-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-3-Carboxylic Acid, 4-(Trifluoromethyl)-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP (current Good Manufacturing Practice) synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.