Description

4-tert-Butyl-1-Iodo-2-Methoxy-Benzene is a high-purity, substituted benzene derivative that serves as a versatile and valuable building block in advanced organic synthesis. Its molecular structure, featuring both an iodine substituent and a tert-butyl group, makes it a critical intermediate for constructing complex molecules through cross-coupling reactions. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing complex aromatic cores via Suzuki-Miyaura, Stille, or other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the iodine atom acts as a handle for introducing diverse functional groups.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands for metal catalysts or as a component in the creation of organocatalysts.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where its substituted aromatic structure can tune electronic properties.
• Chemical Research & Development: A fundamental building block in academic and industrial labs for exploring new synthetic methodologies and creating libraries of compounds for screening.
• Fine Chemical Production: Intermediate in the multi-step synthesis of dyes, pigments, and other performance chemicals requiring specific aromatic architectures.

Basic Information

Product Name	4-tert-Butyl-1-Iodo-2-Methoxy-Benzene
CAS No.	934180-29-7
Molecular Formula	C11H15IO
Molecular Weight	290.14 g/mol
Synonyms	1-Iodo-4-tert-butyl-2-methoxybenzene; 2-Methoxy-4-tert-butyl-1-iodobenzene; 4-(tert-Butyl)-2-methoxy-1-iodobenzene; 4-tert-Butyl-2-methoxyiodobenzene; p-tert-Butyl-o-methoxyiodobenzene; 1-Iodo-2-methoxy-4-tert-butylbenzene
EINECS	Contact for details

Quality Control

Our 4-tert-Butyl-1-Iodo-2-Methoxy-Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming the product meets your specified requirements. Our quality commitment supports applications in cGMP-compliant pharmaceutical development and other high-standard industrial processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability and purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (GC)	≥96.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.