Description

n-[(1S)-2'-Amino[1,1'-Binaphthalen]-2-Yl]-4-Methyl-Benzenesulfonamide is a high-purity, chiral sulfonamide derivative of binaphthyl, a privileged scaffold in asymmetric synthesis. This compound matters as a sophisticated chiral ligand or catalyst precursor for enantioselective transformations, enabling the production of single-enantiomer molecules critical in advanced research and development. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutics, agrochemicals, and specialty materials where precise stereochemical control is paramount.

Application

• Asymmetric Catalysis: Serving as a chiral ligand or catalyst precursor in metal-catalyzed reactions such as hydrogenation, cross-coupling, and C-H activation.
• Pharmaceutical Intermediate: A key building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Research: Used in the development of chiral pesticides and herbicides with enhanced efficacy and environmental profiles.
• Material Science: A precursor for chiral organic frameworks, polymers, or liquid crystals with specific optical properties.
• Academic & Industrial R&D: A valuable tool for method development and discovery chemistry in university and corporate research laboratories.
• Chiral Resolution Agent: Potential use in the separation of enantiomers via diastereomeric salt formation or chromatography.

Basic Information

Product Name	n-[(1S)-2'-Amino[1,1'-Binaphthalen]-2-Yl]-4-Methyl-Benzenesulfonamide
CAS No.	933782-32-2
Molecular Formula	C27H22N2O2S
Molecular Weight	438.54 g/mol
Synonyms	(S)-2'-Amino-2-(p-toluenesulfonamido)-1,1'-binaphthalene; (S)-N-(2'-Amino[1,1'-binaphthalen]-2-yl)-4-methylbenzenesulfonamide; (S)-Tosylamido Binaphthyl Amine; (S)-TsABNA; BINAM-based Sulfonamide Ligand; Chiral Binaphthyl Sulfonamide; (S)-2'-(4-Methylphenylsulfonamido)[1,1'-binaphthalen]-2-amine
EINECS	Contact for details

Quality Control

Our n-[(1S)-2'-Amino[1,1'-Binaphthalen]-2-Yl]-4-Methyl-Benzenesulfonamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity. Keep the container sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.