Description

5-Bromo-1,3,4-Thiadiazole-2-Carboxylic Acid is a high-value heterocyclic building block and key synthetic intermediate prized for its reactive bromine and carboxylic acid functional groups. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. Its primary utility lies in facilitating cross-coupling reactions and serving as a versatile precursor for the synthesis of more complex thiadiazole derivatives.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in antiviral, antibacterial, and anticancer research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiadiazole core.
• Material Science Research: Serves as a monomer or precursor for creating specialty polymers, ligands for catalysis, and organic electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions to create diverse chemical libraries.
• Chemical Biology & Proteomics: Used to develop chemical probes and affinity tags for studying biological systems and protein function.

Basic Information

Product Name	5-Bromo-1,3,4-Thiadiazole-2-Carboxylic Acid
CAS No.	933716-45-1
Molecular Formula	C3HBrN2O2S
Molecular Weight	208.99 g/mol
Synonyms	5-Bromo-1,3,4-thiadiazole-2-carboxylic acid; 2-Bromo-1,3,4-thiadiazole-5-carboxylic Acid; 5-Bromothiadiazole-2-carboxylic Acid; 933716-45-1; 5-Bromo-2-carboxy-1,3,4-thiadiazole; 1,3,4-Thiadiazole-2-carboxylic acid, 5-bromo-; 5-Bromo-1,3,4-thiadiazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,3,4-Thiadiazole-2-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed due to the compound's sensitivity to moisture (hygroscopic nature).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.