Description

2-(Hydroxycyclobutyl)Acetic Acid is a specialized organic compound featuring a cyclobutane ring substituted with both a hydroxyl and an acetic acid functional group, making it a valuable chiral building block for complex synthesis. This structural motif is critical for developing novel active pharmaceutical ingredients (APIs) and advanced materials where precise stereochemistry and molecular geometry are required. It is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including protease inhibitors and other small molecule drugs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides with specific stereochemical activity.
• Fine Chemical Production: Serves as a versatile precursor for synthesizing complex flavors, fragrances, and specialty polymers.
• Material Science Research: Employed in the development of novel monomers for high-performance, stereoregular polymers and resins.
• Academic & Industrial R&D: A critical reagent for methodological studies in organic synthesis, asymmetric catalysis, and chemical biology.

Basic Information

Product Name	2-(Hydroxycyclobutyl)Acetic Acid
CAS No.	933695-45-5
Molecular Formula	C6H10O3
Molecular Weight	130.14 g/mol
Synonyms	2-(Hydroxycyclobutyl)ethanoic acid; (1-Hydroxycyclobut-2-yl)acetic acid; 2-(1-Hydroxycyclobutyl)acetic acid; Cyclobutanol-2-acetic acid; Hydroxycyclobutaneacetic acid; α-(Hydroxycyclobutyl)acetic acid; 933695-45-5
EINECS	Contact for details

Quality Control

Our 2-(Hydroxycyclobutyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high-purity standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.