Description

Imidazo[1,2-B]Pyridazine, 8-Bromo-6-Chloro-3-Fluoro- is a high-purity halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique halogenated imidazopyridazine scaffold.
• Material Science: Serves as a building block for creating novel organic electronic materials, such as OLED (Organic Light-Emitting Diode) components.
• Chemical Biology: Employed as a molecular probe or tag in medicinal chemistry and biochemical research due to its functionalizable halogen groups.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring complex heterocyclic cores.

Basic Information

Product Name	Imidazo[1,2-B]Pyridazine, 8-Bromo-6-Chloro-3-Fluoro-
CAS No.	933035-36-0
Molecular Formula	C7H2BrClFN3
Molecular Weight	276.47 g/mol
Synonyms	8-Bromo-6-chloro-3-fluoroimidazo[1,2-b]pyridazine; 3-Fluoro-8-bromo-6-chloroimidazo[1,2-b]pyridazine; Imidazo[1,2-b]pyridazine, 8-bromo-6-chloro-3-fluoro-; 933035-36-0; 8-Bromo-6-chloro-3-fluoro-[1,2,4]triazolo[4,3-b]pyridazine (common misnomer); Br,Cl,F-Imidazopyridazine; Halogenated Imidazopyridazine Building Block
EINECS	Contact for details

Quality Control

Our Imidazo[1,2-B]Pyridazine, 8-Bromo-6-Chloro-3-Fluoro- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.