Description

2-(3,5-Difluoro-4-Nitrophenyl)Acetic Acid is a high-purity, multi-functional aromatic building block featuring a nitrophenyl core with fluorine substituents. This compound is valued for its role as a critical intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for advanced polymers, liquid crystals, or organic electronic materials due to its aromatic and electron-withdrawing nitro group.
• Chemical Biology Probes: Employed in the design and synthesis of fluorinated probes and tags for imaging and diagnostic applications.
• Organic Synthesis Reagent: A versatile starting material for further functionalization, including reduction of the nitro group or derivatization of the acetic acid moiety.

Basic Information

Item	Details
Product Name	2-(3,5-Difluoro-4-Nitrophenyl)Acetic Acid
CAS No.	932373-91-6
Molecular Formula	C8H5F2NO4
Molecular Weight	217.13 g/mol
Synonyms	2-(3,5-Difluoro-4-nitrophenyl)acetic acid; (3,5-Difluoro-4-nitrophenyl)acetic acid; 4-Nitro-3,5-difluorophenylacetic acid; 2-(4-Nitro-3,5-difluorophenyl)acetic acid; α-Carboxy-3,5-difluoro-4-nitrotoluene; Difluro Nitro Phenyl Acetic Acid; DNPA; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-(3,5-Difluoro-4-Nitrophenyl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment supports applications requiring reliable and traceable raw materials for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.