Description

4-(Trifluoromethyl)-2H,3H,5H,6H,7H-Cyclopenta[C]Pyridazin-3-One is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. Its core value lies in the unique reactivity and physicochemical properties imparted by the trifluoromethyl group and fused ring system, enabling the development of novel compounds with enhanced metabolic stability and bioavailability. This intermediate is critically needed by pharmaceutical and agrochemical R&D teams for the discovery and process development of new active ingredients, particularly in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the CF3 group enhances biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Medicinal Chemistry Scaffold: Provides a privileged structure for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry: Employed in route scouting and scale-up optimization for the commercial production of complex molecules.
• Fluorine Chemistry: Acts as a versatile substrate for further functionalization, exploring the unique effects of fluorine in molecular design.

Basic Information

Product Name	4-(Trifluoromethyl)-2H,3H,5H,6H,7H-Cyclopenta[C]Pyridazin-3-One
CAS No.	929975-31-5
Molecular Formula	C8H7F3N2O
Molecular Weight	204.15 g/mol
Synonyms	4-(Trifluoromethyl)-2,3,5,6,7-pentahydrocyclopenta[c]pyridazin-3-one; 4-(Trifluoromethyl)-3-oxo-2,3,5,6,7-pentahydrocyclopenta[c]pyridazine; Cyclopenta[c]pyridazin-3-one, 4-(trifluoromethyl)-2,3,5,6,7-pentahydro-; 929975-31-5; 4-Trifluoromethyl-2H,3H,5H,6H,7H-cyclopenta[c]pyridazin-3-one; 4-(Trifluoromethyl)cyclopentapyridazinone
EINECS	Contact for details

Quality Control

Our production of 4-(Trifluoromethyl)-2H,3H,5H,6H,7H-Cyclopenta[C]Pyridazin-3-One adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by modern analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.