Description

3-Bromo-4-Fluoro-Benzamidine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. Its core value lies in its bifunctional amidine structure, which serves as a versatile synthon for constructing complex heterocyclic scaffolds and bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly those developing novel kinase inhibitors and other targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially protein kinase inhibitors and other enzyme-targeted small molecules.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated benzamidine core for bioactivity.
• Chemical Biology & Proteomics: Serves as a valuable probe or linker in activity-based protein profiling (ABPP) and bioconjugation strategies due to its reactive amidine group.
• Material Science: Employed in the synthesis of specialized polymers and organic electronic materials where its halogen and nitrogen functionalities can modify material properties.
• Academic & R&D: A fundamental building block for methodological development in organic synthesis and medicinal chemistry research programs.

Basic Information

Product Name	3-Bromo-4-Fluoro-Benzamidine Hydrochloride
CAS No.	929884-81-1
Molecular Formula	C7H7BrClFN2
Molecular Weight	253.50 g/mol
Synonyms	3-Bromo-4-fluorobenzamidine hydrochloride; 3-Bromo-4-fluorobenzenecarboximidamide hydrochloride; 4-Fluoro-3-bromobenzamidine HCl; Benzenecarboximidamide, 3-bromo-4-fluoro-, hydrochloride (1:1); 929884-81-1; 3-Br-4-F-PhC(=NH)NH2·HCl
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Fluoro-Benzamidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.