Description

(E)-3-(2,3-Dichloro-4-(4-Fluorophenylthio)Phenyl)Acrylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a precise building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical manufacturers, biotechnology R&D labs, and fine chemical synthesis specialists focused on developing new drug candidates, particularly in areas requiring specific halogenated and sulfur-containing motifs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step production of target drug molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a crucial building block for structure-activity relationship (SAR) studies and the discovery of new chemical entities in drug discovery programs.
• Biochemical Tool Compound: Used in the development of enzyme inhibitors or receptor modulators, leveraging its specific phenylthio and acrylic acid functional groups.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value organic compounds.
• Agrochemical Intermediate: Potential application in the research and synthesis of novel agrochemicals, such as herbicides or fungicides, due to its dichloro and fluorophenylthio substituents.

Basic Information

Product Name	(E)-3-(2,3-Dichloro-4-(4-Fluorophenylthio)Phenyl)Acrylic Acid
CAS No.	929215-38-3
Molecular Formula	C15H9Cl2FO2S
Molecular Weight	355.20 g/mol
Synonyms	(2E)-3-[2,3-Dichloro-4-[(4-fluorophenyl)sulfanyl]phenyl]prop-2-enoic acid; trans-3-(2,3-Dichloro-4-((4-fluorophenyl)thio)phenyl)acrylic acid; 929215-38-3; (E)-3-(2,3-Dichloro-4-(p-fluorophenylthio)phenyl)acrylic Acid; 3-(2,3-Dichloro-4-((4-fluorophenyl)thio)phenyl)-2-propenoic acid, (E)-
EINECS	Contact for details

Quality Control

Our (E)-3-(2,3-Dichloro-4-(4-Fluorophenylthio)Phenyl)Acrylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and current industry standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.