Description

4-Nitro-3-(Trifluoromethylsulfonyloxy)Benzyl Pivalate is a specialized organic intermediate featuring a nitro group and a trifluoromethanesulfonate (triflate) ester moiety. This compound is of significant value in advanced organic synthesis, particularly as a versatile electrophile or a protected precursor for constructing complex molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring the introduction of nitro or protected benzyl alcohol functionalities.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where its unique structure can contribute to biological activity.
• Cross-Coupling Reactions: Serves as an electrophilic partner in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) due to the reactive triflate leaving group.
• Material Science Precursor: Potential intermediate in the synthesis of advanced organic materials, such as liquid crystals or polymers with specific electronic properties.
• Chemical Biology Probes: Can be utilized in the design and synthesis of molecular probes for studying biological systems.

Basic Information

Product Name	4-Nitro-3-(Trifluoromethylsulfonyloxy)Benzyl Pivalate
CAS No.	929095-35-2
Molecular Formula	C13H14F3NO6S
Molecular Weight	369.32 g/mol
Synonyms	Benzyl alcohol, 4-nitro-3-[[(trifluoromethyl)sulfonyl]oxy]-, 2,2-dimethylpropanoate; 3-(Trifluoromethanesulfonyloxy)-4-nitrobenzyl pivalate; 4-Nitro-3-(triflyloxy)benzyl pivalate; 4-Nitro-3-trifluoromethanesulfonyloxybenzyl pivalate; 4-Nitro-3-OTf-benzyl pivalate; Pivalic acid 4-nitro-3-trifluoromethanesulfonyloxy-benzyl ester
EINECS	Contact for details

Quality Control

Our 4-Nitro-3-(Trifluoromethylsulfonyloxy)Benzyl Pivalate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of our global customer base in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.