Description

Phenol, 5-Ethynyl-2-Nitro- is a specialized aromatic compound featuring both a phenolic hydroxyl group and a nitro substituent, further functionalized with an ethynyl moiety. This unique molecular architecture makes it a valuable high-purity building block for advanced organic synthesis and materials science research. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for constructing complex molecular scaffolds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its specific substitution pattern is required for biological activity.
• Material Science Research: Acts as a precursor for developing specialty polymers, dyes, and advanced organic electronic materials due to its reactive ethynyl group.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological systems, leveraging the "click chemistry" compatibility of the alkyne group.
• Academic & Industrial R&D: A critical reagent for synthetic organic chemists in universities and corporate labs exploring new reaction methodologies and compound libraries.

Basic Information

Product Name	Phenol, 5-Ethynyl-2-Nitro-
CAS No.	928780-90-9
Molecular Formula	C8H5NO3
Molecular Weight	163.13 g/mol
Synonyms	5-Ethynyl-2-nitrophenol; 2-Nitro-5-ethynylphenol; 2-Nitro-5-ethynyl-1-hydroxybenzene; 1-Hydroxy-2-nitro-5-ethynylbenzene; 5-Ethynyl-2-nitro-1-hydroxybenzene; 2-Nitrophenol, 5-ethynyl-; Phenol, 2-nitro-5-ethynyl-
EINECS	Contact for details

Quality Control

Every batch of Phenol, 5-Ethynyl-2-Nitro- is manufactured under strict quality management protocols. Our products undergo rigorous quality testing including HPLC, NMR, and GC-MS to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.