Description

1-(5-Bromopyridin-2-Yl)Pyrrolidin-2-One is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its versatile reactivity, serving as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active small molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials due to its rigid, functionalized structure.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, tags, and linkers for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CMOs for client-specific synthesis projects requiring specialized bromopyridine derivatives.
• Academic Research: Used in university and institutional labs for methodological development and exploration of new chemical reactions.

Basic Information

Product Name	1-(5-Bromopyridin-2-Yl)Pyrrolidin-2-One
CAS No.	928775-04-6
Molecular Formula	C9H9BrN2O
Molecular Weight	241.09 g/mol
Synonyms	1-(5-Bromo-2-pyridinyl)-2-pyrrolidinone; 2-Pyrrolidinone, 1-(5-bromo-2-pyridinyl)-; 5-Bromo-2-(2-oxopyrrolidin-1-yl)pyridine; 1-(5-Bromopyridin-2-yl)pyrrolidin-2-one; 928775-04-6; 5-Bromo-1H-pyrrolo[2,3-b]pyridine (Note: This is a common mis-assignment, verify structure); 5-Bromo-2-(pyrrolidin-1-yl)pyridine (related compound, verify)
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyridin-2-Yl)Pyrrolidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.