Description

4-Bromo-1-Chloro-2-(Chloromethyl)Benzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its multi-functional structure, featuring bromo, chloro, and chloromethyl substituents, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated benzyl moiety.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where its halogenated structure contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the creation of monomers and functionalized polymers with specific electronic or structural properties.
• Organic Synthesis Building Block: Utilized in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to introduce functionalized aryl groups.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways and creating compound libraries for screening.

Basic Information

Product Name	4-Bromo-1-Chloro-2-(Chloromethyl)Benzene
CAS No.	928758-19-4
Molecular Formula	C7H5BrCl2
Molecular Weight	239.93 g/mol
Synonyms	2-(Chloromethyl)-4-bromo-1-chlorobenzene; 1-Bromo-4-chloro-2-(chloromethyl)benzene; 4-Bromo-2-(chloromethyl)-1-chlorobenzene; 2-Chloromethyl-4-bromo-1-chlorobenzene; 4-Bromo-1-chloro-2-chloromethylbenzene; Benzene, 4-bromo-1-chloro-2-(chloromethyl)-; α,2,4-Trichlorobromotoluene (related structure)
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Chloro-2-(Chloromethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.