Description

1-(Bromomethyl)-3-Methoxy-5-Nitrobenzene is a versatile brominated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a reactive bromomethyl group and a nitro substituent, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a functionalized benzyl or aryl moiety.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex nitro- and methoxy-substituted dyes and organic pigments.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for creating biaryl structures.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags due to its reactive bromomethyl handle for bioconjugation.

Basic Information

Product Name	1-(Bromomethyl)-3-Methoxy-5-Nitrobenzene
CAS No.	928664-12-4
Molecular Formula	C8H8BrNO3
Molecular Weight	246.06 g/mol
Synonyms	3-Methoxy-5-nitrobenzyl bromide; (3-Methoxy-5-nitrophenyl)methyl bromide; 5-Nitro-3-methoxybenzyl bromide; 1-Bromomethyl-3-methoxy-5-nitrobenzene; α-Bromo-3-methoxy-5-nitrotoluene; NSC 405124; AI3-52311
EINECS	Contact for details

Quality Control

Our 1-(Bromomethyl)-3-Methoxy-5-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This compound is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.