Description

(1,1-Dioxidotetrahydro-2H-Thiopyran-4-Yl)Methyl 4-Methylbenzenesulfonate is a high-purity sulfonate ester derivative, serving as a critical building block and reactive intermediate in advanced organic synthesis. Its value lies in its ability to act as a versatile alkylating or functionalizing agent, enabling the precise construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates containing sulfone or sulfonate moieties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Polymer Chemistry: Functional monomer or cross-linking agent in the production of specialty polymers with specific thermal or chemical resistance properties.
• Material Science Research: Employed in the development of advanced materials, such as liquid crystals or organic semiconductors.
• Chemical Biology Probes: Useful for synthesizing molecular probes to study enzyme activity or biological pathways.

Basic Information

Product Name	(1,1-Dioxidotetrahydro-2H-Thiopyran-4-Yl)Methyl 4-Methylbenzenesulfonate
CAS No.	928149-12-6
Molecular Formula	C13H18O5S2
Molecular Weight	318.41 g/mol
Synonyms	4-(Tosyloxymethyl)tetrahydro-2H-thiopyran 1,1-dioxide; (Tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)methyl 4-methylbenzenesulfonate; 4-(Hydroxymethyl)tetrahydro-2H-thiopyran 1,1-dioxide tosylate; Thiopyran sulfone tosylate derivative; Tosyloxymethyl tetrahydrothiopyran dioxide; Sulfolane tosylate derivative; Contact for details on additional trade names or abbreviations.
EINECS	Contact for details

Quality Control

Our (1,1-Dioxidotetrahydro-2H-Thiopyran-4-Yl)Methyl 4-Methylbenzenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.