Description

3-Bromo-6-Morpholinopyridazine is a high-value, functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a bromo substituent and a morpholine ring, which provides versatile handles for further derivatization via cross-coupling and substitution reactions. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the construction of novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for creating functional organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to introduce complex substituents.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries in medicinal chemistry for high-throughput screening.

Basic Information

Product Name	3-Bromo-6-Morpholinopyridazine
CAS No.	927673-86-7
Molecular Formula	C8H10BrN3O
Molecular Weight	244.09 g/mol
Synonyms	3-Bromo-6-morpholinopyridazine; 6-Morpholino-3-bromopyridazine; 3-Bromo-6-(4-morpholinyl)pyridazine; Pyridazine, 3-bromo-6-morpholino-; 927673-86-7; 3-Br-6-Morpholinopyridazine
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Morpholinopyridazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.