Description

2-Methoxy-4-(Tributylstannyl)Thiazole is a specialized organotin reagent featuring a functionalized thiazole heterocycle. This compound is valued for its role as a key synthetic intermediate in advanced organic transformations, particularly in cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing thiazole or organometallic motifs.
• Agrochemical Synthesis: Serves as a building block for creating novel fungicides, herbicides, and insecticides with enhanced efficacy.
• Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and other functional materials.
• Stille Cross-Coupling Reactions: Acts as a crucial organotin reagent for the efficient formation of carbon-carbon bonds under mild conditions.
• Ligand and Catalyst Development: Used to prepare novel ligands and organometallic catalysts for asymmetric synthesis and polymerization processes.
• Chemical Biology Probes: Facilitates the synthesis of labeled compounds and probes for studying biological mechanisms.

Basic Information

Product Name	2-Methoxy-4-(Tributylstannyl)Thiazole
CAS No.	927391-09-1
Molecular Formula	C16H31NOSSn
Molecular Weight	404.21 g/mol
Synonyms	4-(Tributylstannyl)-2-methoxythiazole; Tributyl(2-methoxy-4-thiazolyl)stannane; 2-Methoxy-4-(tributylstannyl)-1,3-thiazole; Stannane, tributyl(2-methoxy-4-thiazolyl)-; 2-Methoxy-4-tributylstannylthiazole; 4-Tributylstannyl-2-methoxythiazole
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-(Tributylstannyl)Thiazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Purity (NMR)	Conforms
Tin (Sn) Content	29.0 - 30.0 %
Water Content (KF)	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.