Description

1-(Propan-2-Yl)-1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fused pyrazolopyridine core enables the creation of complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides with novel modes of action.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular tools to study biological pathways and protein functions.
• Material Science Research: Investigated as a building block for organic electronic materials or metal-organic frameworks (MOFs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	1-(Propan-2-Yl)-1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid
CAS No.	923689-61-6
Molecular Formula	C10H11N3O2
Molecular Weight	205.21 g/mol
Synonyms	1-Isopropyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid; 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid, 1-(1-methylethyl)-; 1-(Propan-2-yl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid; 1-Isopropyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid; 923689-61-6; 1-(1-Methylethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-(Propan-2-Yl)-1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.