Description

1H-Pyrazole-1-Sulfonamide, N,n-Dimethyl-3-(Trifluoromethyl)- CAS NO 922516-21-0 is a high-purity, functionalized pyrazole derivative characterized by its sulfonamide and trifluoromethyl groups. This compound is a valuable specialty chemical intermediate for advanced synthesis, offering unique reactivity and physicochemical properties. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Material Science Research: Used in the development of advanced polymers and functional materials where specific sulfonamide chemistry is required.
• Chemical Biology & Proteomics: Acts as a versatile scaffold or linker in the design of chemical probes and enzyme inhibitors for biological research.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up development.

Basic Information

Product Name	1H-Pyrazole-1-Sulfonamide, N,n-Dimethyl-3-(Trifluoromethyl)-
CAS No.	922516-21-0
Molecular Formula	C6H8F3N3O2S
Molecular Weight	243.21 g/mol
Synonyms	N,N-Dimethyl-3-(trifluoromethyl)-1H-pyrazole-1-sulfonamide; 3-(Trifluoromethyl)-N,N-dimethyl-1H-pyrazole-1-sulfonamide; 1H-Pyrazole-1-sulfonamide, N,N-dimethyl-3-(trifluoromethyl)-; N,N-Dimethyl-3-trifluoromethylpyrazole-1-sulfonamide; Dimethyl-[3-(trifluoromethyl)pyrazol-1-yl]sulfonyl]amine; 922516-21-0
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrazole-1-Sulfonamide, N,n-Dimethyl-3-(Trifluoromethyl)- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the rigorous demands of GMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure the container is kept tightly sealed to prevent degradation from atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.