Description

2,5,7,10-Tetraazaundecanedioic Acid, 3,9-Dimethyl-6-Thioxo-, 1,11-Bis(1,1-Dimethylethyl) Ester, (3S,9S)- is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for drug candidates.
• Peptidomimetic Synthesis: Serves as a constrained scaffold in the design of peptide analogs and mimetics.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or ligand precursor in catalytic asymmetric transformations.
• Chemical Biology: Employed in the synthesis of molecular probes for studying biological pathways and target engagement.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	2,5,7,10-Tetraazaundecanedioic Acid, 3,9-Dimethyl-6-Thioxo-, 1,11-Bis(1,1-Dimethylethyl) Ester, (3S,9S)-
CAS No.	922495-32-7
Molecular Formula	C19H36N4O4S
Molecular Weight	416.58 g/mol
Synonyms	(3S,9S)-1,11-Di-tert-butyl 3,9-dimethyl-6-thioxo-2,5,7,10-tetraazaundecanedioate; 1,11-Bis(1,1-dimethylethyl) (3S,9S)-3,9-dimethyl-6-thioxo-2,5,7,10-tetraazaundecanedioate; (3S,9S)-Di-tert-butyl 3,9-dimethyl-6-thioxo-2,5,7,10-tetraazaundecanedioate; Chiral tetraazaundecanedioate derivative; Thioxo-tetraaza bis-tert-butyl ester; Advanced chiral intermediate 922495-32-7; Stereoisomer of C19H36N4O4S
EINECS	Contact for details

Quality Control

Our 2,5,7,10-Tetraazaundecanedioic Acid, 3,9-Dimethyl-6-Thioxo-, 1,11-Bis(1,1-Dimethylethyl) Ester, (3S,9S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (3S,9S)-isomer
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.