Description

Epoxide Polymer-Bound, Copolymer Of Methacrylamide, N,N'-Methylen-Bis(Acrylamide) And A Monomer Carrying Oxirane Groups is a specialized functional polymer resin designed for covalent immobilization and purification applications. This material matters because its reactive oxirane (epoxide) groups provide a versatile platform for the stable, single-point attachment of ligands containing nucleophilic functional groups like amines or thiols. Industrial and academic researchers in life sciences and chemical synthesis need this robust, beaded support for creating affinity chromatography media, solid-phase synthesis resins, and enzyme immobilization matrices.

Application

• Affinity Chromatography Media: Primary use for the purification of antibodies, proteins, and other biomolecules by coupling specific ligands (e.g., Protein A, dyes, metal chelates) to the epoxide-activated matrix.
• Enzyme & Catalyst Immobilization: Covalent binding of enzymes, whole cells, or chemical catalysts to create reusable, stable biocatalysts for industrial bioprocesses and green chemistry.
• Solid-Phase Synthesis Support: Serving as a functionalized resin for peptide synthesis, oligonucleotide synthesis, or combinatorial chemistry library generation.
• Diagnostic & Biosensor Development: Immobilization of capture probes (antibodies, DNA) onto beads or surfaces for diagnostic assays and sensor platforms.
• Ligand Fishing & Target Identification: Used in proteomics and drug discovery to isolate binding partners from complex biological mixtures.
• Water Treatment & Metal Chelation: Functionalization with chelating agents to create resins for the selective removal of heavy metals from industrial wastewater.

Basic Information

Item	Details
Product Name	Epoxide Polymer-Bound, Copolymer Of Methacrylamide, N,N'-Methylen-Bis(Acrylamide) And A Monomer Carrying Oxirane Groups
CAS No.	920278-43-9
Molecular Formula	Proprietary Polymer
Molecular Weight	N/A (Macromolecular Resin)
Synonyms	Epoxy-activated methacrylamide copolymer; Oxirane-functionalized poly(methacrylamide-co-N,N'-methylenebisacrylamide); Glycidyl methacrylate copolymer support; Epoxide-activated beaded resin; Reactive polymer support for immobilization; Affinity chromatography matrix, epoxide-activated; Polymeric epoxide carrier; GMA-based activated resin.
EINECS	Contact for details

Quality Control

Our epoxide-activated polymer resins are manufactured under a strict quality management system. Each batch is characterized for critical parameters including epoxide group density, particle size distribution, swelling behavior, and mechanical stability to ensure consistent performance in demanding separation and synthesis applications. Certificates of Analysis (COA) detailing these specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The resin is stable under these conditions but prolonged exposure to high humidity should be avoided. Keep away from strong acids and organic solvents prior to coupling, as these may prematurely react with or degrade the active epoxide groups.

Specification

Item	Specification
Appearance	White to off-white spherical beads
Matrix	Poly(methacrylamide-co-N,N'-methylenebisacrylamide)
Functional Group	Oxirane (Epoxide)
Epoxide Group Density	100 - 500 µmol/g (dry resin)
Particle Size	45-150 µm (or as specified)
Swelling	Approx. 3-6 mL/g in water
Exclusion Limit	> 1 x 10⁶ Daltons
Storage Stability	> 12 months at recommended conditions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.