Description

3-Aminotetrahydrofuran-3-Carboxylic Acid Hydrochloride is a high-purity, non-proteinogenic amino acid derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique constrained furanoid ring structure and functional groups make it a valuable scaffold for constructing complex molecules with precise stereochemistry. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including protease inhibitors and other bioactive molecules.
• Peptidomimetics & Constrained Peptide Design: Used to introduce conformational rigidity into peptide backbones, enhancing metabolic stability and binding affinity in drug discovery.
• Agrochemical Synthesis: Serves as a building block for creating novel, chiral active ingredients for crop protection products.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tools for studying biological pathways and enzyme mechanisms.
• Ligand & Catalyst Development: Useful for constructing chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & Contract Research: A valuable reagent for methodological development and synthetic chemistry research in academic and CRO laboratories.

Basic Information

Product Name	3-Aminotetrahydrofuran-3-Carboxylic Acid Hydrochloride
CAS No.	919098-94-5
Molecular Formula	C5H10ClNO3
Molecular Weight	167.59 g/mol
Synonyms	3-Aminooxolane-3-carboxylic acid hydrochloride; 3-Aminotetrahydro-3-furancarboxylic acid hydrochloride; (3R/S)-3-Aminotetrahydrofuran-3-carboxylic acid hydrochloride; 3-Amino-3-carboxytetrahydrofuran hydrochloride; ATFC-HCl; 3-ATFC HCl; Tetrahydro-3-furanoic acid, 3-amino-, hydrochloride; Furan-3-carboxylic acid, 3-amino-, hydrochloride, tetrahydro-
EINECS	Contact for details

Quality Control

Our 3-Aminotetrahydrofuran-3-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.