Description

Methyl 2,3,4-Triacetyl-D-Glucopyranosiduronyl 1-(n-4-Metoxyphenyl)-2,2,2-Trifluoroacetimidate is a sophisticated, high-purity glycosyl donor building block critical for synthetic carbohydrate chemistry. Its primary value lies in enabling the precise and efficient synthesis of complex oligosaccharides and glycoconjugates, which are essential for advanced pharmaceutical research. This compound is specifically designed for use by researchers and process chemists in the pharmaceutical, biotechnology, and fine chemical industries, particularly those developing novel therapeutics, vaccines, and diagnostic agents. The CAS number for this compound is 918158-52-8.

Application

• Glycosylation Reagent: A key intermediate for the stereoselective synthesis of complex oligosaccharides and glycans.
• Pharmaceutical Intermediate: Used in the research and development of carbohydrate-based drugs, including antiviral and anticancer agents.
• Glycoconjugate Synthesis: Essential for creating glycoproteins, glycolipids, and other biologically active conjugates for immunological studies.
• Carbohydrate Chemistry Research: A vital tool in academic and industrial laboratories for exploring new synthetic pathways and glycosidic bond formation.
• Biomimetic Compound Development: Facilitates the creation of synthetic analogs of natural carbohydrates for structure-activity relationship (SAR) studies.
• Vaccine Adjuvant Development: Potential use in synthesizing carbohydrate components for next-generation vaccine formulations.

Basic Information

Item	Detail
Product Name	Methyl 2,3,4-Triacetyl-D-Glucopyranosiduronyl 1-(n-4-Metoxyphenyl)-2,2,2-Trifluoroacetimidate
CAS No.	918158-52-8
Molecular Formula	C22H24F3NO11
Molecular Weight	535.42 g/mol
Synonyms	Methyl (2,3,4-tri-O-acetyl-α-D-glucopyranosyluronate) 1-(4-methoxyphenyl)-2,2,2-trifluoroacetimidate; 4-Methoxyphenyl 2,3,4-tri-O-acetyl-1-deoxy-1-[(2,2,2-trifluoroacetimidoyl)oxy]-α-D-glucopyranuronate; Glycosyl Donor Trifluoroacetimidate; Glucuronic Acid Trifluoroacetimidate Derivative; TFAI Glycosylation Donor; Methyl 2,3,4-Tri-O-acetyl-α-D-glucopyranosyluronate Trifluoroacetimidate
EINECS	Contact for details

Quality Control

Every batch of Methyl 2,3,4-Triacetyl-D-Glucopyranosiduronyl 1-(n-4-Metoxyphenyl)-2,2,2-Trifluoroacetimidate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and other spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.