Description

2-Phenyl-6-(trifluoromethyl)-4,5-dihydropyridazin-3(2H)-one is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of a dihydropyridazinone scaffold and a trifluoromethyl group, which are critical for modulating the physicochemical and biological properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with specific thermal or surface properties.
• Chemical Biology Probe: Employed in the design of molecular probes to study enzyme mechanisms or protein-ligand interactions.
• Fluorine Chemistry Library Synthesis: A crucial building block for constructing diverse compound libraries focused on fluorine-containing molecules for high-throughput screening.

Basic Information

Product Name	2-Phenyl-6-(trifluoromethyl)-4,5-dihydropyridazin-3(2H)-one
CAS No.	916909-01-8
Molecular Formula	C11H9F3N2O
Molecular Weight	242.20 g/mol
Synonyms	2-Phenyl-6-(trifluoromethyl)-4,5-dihydro-3(2H)-pyridazinone; 6-(Trifluoromethyl)-2-phenyl-4,5-dihydro-3(2H)-pyridazinone; 2-Phenyl-6-(trifluoromethyl)-2,4,5,6-tetrahydropyridazin-3-one; 3(2H)-Pyridazinone, 4,5-dihydro-2-phenyl-6-(trifluoromethyl)-; 916909-01-8
EINECS	Contact for details

Quality Control

Our 2-Phenyl-6-(trifluoromethyl)-4,5-dihydropyridazin-3(2H)-one is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.