Description

3-[3-Chloro-5-(Trifluoromethoxy)Phenyl]Propionic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its unique molecular architecture, combining a phenylpropionic acid backbone with chloro and trifluoromethoxy substituents, which are critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the trifluoromethoxy group enhances lipophilicity and biological activity.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in electronic display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of electron-transport or host materials for improved device efficiency.
• Advanced Polymer Chemistry: Acts as a monomer or modifier for introducing fluorine into specialty polymers to alter surface properties and chemical resistance.
• Chemical Research & Development: A versatile building block for exploring structure-activity relationships (SAR) in medicinal and material science.

Basic Information

Product Name	3-[3-Chloro-5-(Trifluoromethoxy)Phenyl]Propionic Acid
CAS No.	916420-74-1
Molecular Formula	C10H8ClF3O3
Molecular Weight	268.62 g/mol
Synonyms	3-(3-Chloro-5-(trifluoromethoxy)phenyl)propanoic acid; 3-(3-Chloro-5-(trifluoromethoxy)phenyl)propionic Acid; 3-Chloro-5-(trifluoromethoxy)benzenepropanoic Acid; 916420-74-1; 3-[3-Chloro-5-(trifluoromethoxy)phenyl]propanoic acid; 3-(3-Chloro-5-(trifluoromethoxyphenyl))propionic Acid
EINECS	Contact for details

Quality Control

Our 3-[3-Chloro-5-(Trifluoromethoxy)Phenyl]Propionic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.