Description

n-(2-Succinyl) Phenylephrine is a chemically modified derivative of the well-known α-adrenergic agonist, phenylephrine. This succinylated analog is primarily utilized as a key synthetic intermediate in the research and development of novel pharmaceutical compounds. It is of significant interest to researchers and manufacturers in the pharmaceutical and biotechnology sectors who are developing advanced drug delivery systems and prodrug formulations. The compound offers a versatile chemical handle for further conjugation and modification.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of new active pharmaceutical ingredients (APIs) and prodrug candidates.
• Prodrug Development: Used in research to create prodrug forms of phenylephrine or related compounds, aiming to modify pharmacokinetic properties such as absorption and duration of action.
• Bioconjugation Research: Acts as a linker or precursor for conjugating pharmacologically active molecules to carriers like polymers, proteins, or nanoparticles.
• Chemical Biology Studies: Employed in biochemical research to investigate receptor-ligand interactions and signal transduction pathways involving adrenergic receptors.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	n-(2-Succinyl) Phenylephrine
CAS No.	915278-80-7
Molecular Formula	C19H21NO6
Molecular Weight	359.38 g/mol
Synonyms	Phenylephrine Succinate Derivative; 2-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-3-(3-hydroxyphenyl)propanoic Acid, 4-Oxo-; Succinyl Phenylephrine; N-Succinylphenylephrine; (R)-3-[3-Hydroxyphenyl]-2-[(methylamino)methyl]-4-oxobutanoic Acid; 915278-80-7; Phenylephrine N-Succinyl Ester
EINECS	Contact for details

Quality Control

Our n-(2-Succinyl) Phenylephrine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods and purity assessment by HPLC, to ensure it meets high-purity standards suitable for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming batch-specific results for identity, purity, and impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.