Description

L-Glutamic Acid, 5-Cyclohexyl 1-(Phenylmethyl) Ester is a specialized, high-purity chemical intermediate designed for advanced synthesis. This compound is valued for its unique molecular architecture, which incorporates protected glutamic acid and benzyl functionalities, making it a critical building block for complex organic transformations. It is primarily required by research institutions and pharmaceutical development teams working on peptide mimetics, prodrug development, and novel bioactive molecule synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex peptide analogs and targeted drug candidates.
• Prodrug Development: Utilized to create ester-based prodrugs designed for improved bioavailability and targeted release.
• Bioconjugation Chemistry: Serves as a versatile linker or spacer molecule in antibody-drug conjugates (ADCs) and other bioconjugates.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing molecules with specific chiral centers and functional groups.
• Biochemical Research: Used in studies exploring enzyme inhibitors, receptor ligands, and metabolic pathway modulators.

Basic Information

Product Name	L-Glutamic Acid, 5-Cyclohexyl 1-(Phenylmethyl) Ester
CAS No.	915194-00-2
Molecular Formula	C18H25NO4
Molecular Weight	319.40 g/mol
Synonyms	5-Cyclohexyl 1-Benzyl L-Glutamate; 1-Benzyl 5-cyclohexyl L-glutamate; L-Glutamic acid, 5-cyclohexyl ester, 1-(phenylmethyl) ester; Benzyl 5-cyclohexyl L-glutamate; Glutamic acid benzyl ester cyclohexyl ester; (S)-5-Cyclohexyl 1-benzyl glutamate; N-Benzyloxycarbonyl-5-cyclohexyl-L-glutamate
EINECS	Contact for details

Quality Control

Our L-Glutamic Acid, 5-Cyclohexyl 1-(Phenylmethyl) Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification, to ensure it meets the exacting standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.