Description

3,3-Dichlorocyclobutanecarboxylic Acid is a versatile and highly functionalized cyclobutane derivative, serving as a critical building block in advanced organic synthesis. Its unique strained-ring structure, combined with reactive carboxylic acid and dichloro substituents, makes it a valuable precursor for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to develop novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the cyclobutane core can contribute to unique biological activity and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts, enabling asymmetric synthesis in fine chemical manufacturing.
• Polymer Chemistry: Incorporated as a monomer or cross-linking agent to create specialty polymers with enhanced thermal stability or specific mechanical properties.
• Chemical Research & Development: Employed in academic and industrial R&D for studying ring-strain reactivity and developing new synthetic methodologies.
• Material Science: Investigated for use in the synthesis of advanced organic electronic materials and liquid crystals.

Basic Information

Product Name	3,3-Dichlorocyclobutanecarboxylic Acid
CAS No.	915185-89-6
Molecular Formula	C5H6Cl2O2
Molecular Weight	168.99 g/mol
Synonyms	3,3-Dichlorocyclobutanecarboxylic Acid; Cyclobutanecarboxylic acid, 3,3-dichloro-; 3,3-Dichlorocyclobutane-1-carboxylic acid; 1-Carboxy-3,3-dichlorocyclobutane; 915185-89-6; 3,3-Dichloro-cyclobutanecarboxylic acid; 3,3-Dichlorocyclobutylcarboxylic acid
EINECS	Contact for details

Quality Control

Our 3,3-Dichlorocyclobutanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, ensure containers are made of compatible materials and are properly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.