Description

6-Chloro-1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique pyrrolopyridine scaffold, which is a privileged structure in medicinal chemistry for designing bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel small-molecule drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, anticancer agents, and other therapeutic compounds targeting the pyrrolopyridine pharmacophore.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a starting material for creating specialized ligands, organic semiconductors, and functional polymers.
• Academic & Contract Research: A valuable reagent for method development, library synthesis, and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Bioconjugation Chemistry: The carboxylic acid group enables coupling reactions for creating protein-drug conjugates or diagnostic probes.

Basic Information

Product Name	6-Chloro-1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid
CAS No.	915140-96-4
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	6-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid; 6-Chloro-3-carboxy-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylate; 915140-96-4; 6-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid (CAS 915140-96-4); 6-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid, 6-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid (6-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid)
EINECS	Contact for details

Quality Control

Our 6-Chloro-1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.