Description

6-(2,2-Difluoro-2-Phenylethoxy)Hexan-1-Amine is a specialized bifunctional organic compound featuring a primary amine and a difluorinated phenylethoxy chain, making it a valuable building block in advanced organic synthesis. Its molecular architecture is engineered to serve as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorinated motifs and amine-linked functionalities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially those requiring fluorinated aromatic ether and amine linkages for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the difluoro and ether-amine structure can contribute to specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed to introduce amine functional groups and fluorinated side chains into polymer backbones, altering surface properties and chemical resistance.
• Material Science Research: Utilized in the development of advanced organic electronic materials, liquid crystals, and specialty surfactants.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	6-(2,2-Difluoro-2-Phenylethoxy)Hexan-1-Amine
CAS No.	915132-93-3
Molecular Formula	C14H21F2NO
Molecular Weight	257.32 g/mol
Synonyms	6-(2,2-Difluoro-2-phenylethoxy)hexan-1-amine; 1-Hexanamine, 6-[2,2-difluoro-2-phenylethoxy]-; 6-(2,2-Difluoro-2-phenylethoxy)hexylamine; 2,2-Difluoro-2-phenylethoxyhexylamine; Hexane-1,6-diamine derivative; DFPEHA; Amine-terminated fluorinated ether; (6-Aminohexyloxy)(2,2-difluoro-2-phenyl)ethane
EINECS	Contact for details

Quality Control

Our 6-(2,2-Difluoro-2-Phenylethoxy)Hexan-1-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring consistency and reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.