Description

Acetoxy Empagliflozin CAS NO 915095-99-7 is a key pharmaceutical intermediate in the synthesis of the active pharmaceutical ingredient (API) Empagliflozin, a leading SGLT2 inhibitor. This high-purity compound is critical for ensuring the final drug product meets stringent pharmacopeial standards for efficacy and safety. It is primarily required by pharmaceutical manufacturers and advanced research institutions engaged in the development and production of next-generation anti-diabetic medications.

Application

• Primary Intermediate in the commercial synthesis of the API Empagliflozin.
• Process Development for optimizing scalable and cost-effective manufacturing routes for SGLT2 inhibitors.
• Analytical Reference Standard for quality control and method validation in API production.
• Research & Development of novel Empagliflozin analogs and related therapeutic compounds.
• GMP Manufacturing for the production of regulated, finished dosage forms.
• Contract Manufacturing Organizations (CMOs) supplying intermediates to the global pharmaceutical supply chain.

Basic Information

Product Name	Acetoxy Empagliflozin
CAS No.	915095-99-7
Molecular Formula	C25H27ClO8
Molecular Weight	491.93 g/mol
Synonyms	Empagliflozin Acetate; Empagliflozin 2',3',4',6'-Tetraacetate; (2S,3R,4R,5S,6R)-2-[4-Chloro-3-[[4-[[(3S)-oxolan-3-yl]oxy]phenyl]methyl]phenyl]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triyl triacetate; BI 10773 Acetoxy Intermediate; 1-Chloro-4-(β-D-glucopyranos-1-yl)-2-[4-((S)-tetrahydrofuran-3-yloxy)benzyl]benzene Tetraacetate
EINECS	Contact for details

Quality Control

Our Acetoxy Empagliflozin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical synthesis. Quality is verified through comprehensive analytical testing, including HPLC, NMR, and MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support compliance with ICH Q7 guidelines and can tailor specifications to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.