Description

D-Glucitol, 1,5-Anhydro-1-C-[4-Chloro-3-[[4-[[(3R)-Tetrahydro-3-Furanyl]Oxy]Phenyl]Methyl]Phenyl]-, Tetraacetate, (1S)- (9Ci) is a sophisticated, high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key chiral building block in the synthesis of complex bioactive molecules. It is primarily sought after by R&D teams and process chemists in the pharmaceutical and fine chemical industries working on novel therapeutic agents, particularly in metabolic and cardiovascular disease research.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the multi-step synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of novel small-molecule therapeutics.
• Process Chemistry: Serves as a standardized building block for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Metabolic Research: Potential applications in developing compounds targeting metabolic pathways and enzyme inhibition.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, high-value specialty chemicals for advanced material science.

Basic Information

Product Name	D-Glucitol, 1,5-Anhydro-1-C-[4-Chloro-3-[[4-[[(3R)-Tetrahydro-3-Furanyl]Oxy]Phenyl]Methyl]Phenyl]-, Tetraacetate, (1S)- (9Ci)
CAS No.	915095-98-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3R)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol tetraacetate; 1,5-Anhydro-1-C-[4-chloro-3-[(4-[(3R)-oxolan-3-yloxy]phenyl)methyl]phenyl]-D-glucitol tetraacetate; Canagliflozin Tetraacetate Impurity; SGLT2 Inhibitor Intermediate; Canagliflozin Related Compound Tetraacetate; (1S)-Canagliflozin Tetraacetate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Quality is verified through modern analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support development and commercial projects with material suitable for research use or produced under quality management systems aligned with ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be incompatible with strong alkali/organic solvent. Keep the container tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.