Description

4-[3-(4-Cyano-3-Trifluoromethylphenyl)-5,5-Dimethyl-4-Oxo-2-Thioxoimidazolidin-1-Yl]-n-Methylbenzamide is a high-purity, non-steroidal androgen receptor antagonist with a complex heterocyclic structure, designed for advanced pharmaceutical research and development. Its core value lies in its potent and selective biological activity, making it a critical intermediate or active pharmaceutical ingredient (API) for developing novel therapeutic agents. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on endocrinology, oncology, and metabolic disease treatments.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of next-generation androgen receptor-targeting therapeutics.
• Research Chemical: Used in biochemical and pharmacological studies to investigate androgen receptor signaling pathways and mechanisms of action.
• Preclinical Development: Employed in the formulation and testing of drug candidates for conditions like prostate cancer, benign prostatic hyperplasia, and androgenetic alopecia.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in API manufacturing.
• Chemical Biology Probe: Utilized to study protein-ligand interactions and for target validation in drug discovery programs.

Basic Information

Product Name	4-[3-(4-Cyano-3-Trifluoromethylphenyl)-5,5-Dimethyl-4-Oxo-2-Thioxoimidazolidin-1-Yl]-n-Methylbenzamide
CAS No.	915087-16-0
Molecular Formula	C21H16F3N5O2S
Molecular Weight	459.45 g/mol
Synonyms	Bicalutamide Impurity; Bicalutamide Related Compound; 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide; 1-[4-(Methylcarbamoyl)phenyl]-3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-2-thioxoimidazolidin-4-one; Androgen Receptor Antagonist (Bicalutamide Derivative); CAS 915087-16-0
EINECS	Contact for details

Quality Control

Our 4-[3-(4-Cyano-3-Trifluoromethylphenyl)-5,5-Dimethyl-4-Oxo-2-Thioxoimidazolidin-1-Yl]-n-Methylbenzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.