Description

1-(3-Chloro-4-Fluorophenyl)Biguanide Hydrochloride is a high-purity pharmaceutical intermediate and research chemical. This compound is valued for its role as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring biguanide-based structures. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel biguanide-based drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• Antimicrobial Agent Development: Serves as a core structure for research into new antibacterial and antifungal compounds.
• Chemical Synthesis: Employed in organic synthesis to introduce the (3-chloro-4-fluorophenyl)biguanide moiety into more complex molecules.
• Biochemical Research: Used as a tool compound in biochemical assays to study enzyme inhibition and metabolic pathways.

Basic Information

Product Name	1-(3-Chloro-4-Fluorophenyl)Biguanide Hydrochloride
CAS No.	915071-41-9
Molecular Formula	C8H9ClF N5 • HCl
Molecular Weight	278.55 g/mol
Synonyms	1-(3-Chloro-4-fluorophenyl)biguanide monohydrochloride; N-(3-Chloro-4-fluorophenyl)imidodicarbonimidic diamide hydrochloride; 3-Chloro-4-fluoro-1-biguanidinobenzene hydrochloride; (3-Chloro-4-fluorophenyl)biguanide HCl; Biguanide, 1-(3-chloro-4-fluorophenyl)-, monohydrochloride; 915071-41-9; N-(3-Chloro-4-fluorophenyl)guanylguanidine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3-Chloro-4-Fluorophenyl)Biguanide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay, impurity profile, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.