Description

1,3-Dibromo-5-Isopropyl-2-Methoxybenzene is a high-purity, multi-functional brominated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique substitution pattern, which provides strategic sites for further functionalization and cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries to create novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated aromatic core.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the bromine atoms serve as handles for further derivatization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphine or nitrogen-based ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or monomers for conjugated polymers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions to form biaryl structures.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CMOs for client-directed research and scale-up projects.

Basic Information

Product Name	1,3-Dibromo-5-Isopropyl-2-Methoxybenzene
CAS No.	915069-01-1
Molecular Formula	C10H12Br2O
Molecular Weight	308.01 g/mol
Synonyms	2-Methoxy-1,3-dibromo-5-isopropylbenzene; 5-Isopropyl-1,3-dibromo-2-methoxybenzene; 1,3-Dibromo-5-(1-methylethyl)-2-methoxybenzene; 2-Methoxy-5-isopropyl-1,3-dibromobenzene; Benzene, 1,3-dibromo-5-(1-methylethyl)-2-methoxy-; Dibromoisopropylmethoxybenzene
EINECS	Contact for details

Quality Control

Our 1,3-Dibromo-5-Isopropyl-2-Methoxybenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality documentation to meet specific client and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.