Description

3α-Hydroxy-6-Ethyl-7-Keto-5β-Cholan-24-Oic Acid is a high-purity steroidal bile acid derivative, a key intermediate in advanced pharmaceutical synthesis. This compound is valued for its specific molecular framework, which is crucial for developing targeted therapeutic agents and conducting metabolic pathway research. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel steroid-based drugs, metabolic regulators, and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in studies of bile acid metabolism, liver function, and related biochemical pathways.
• Fine Chemical Synthesis: Serves as a specialized precursor for creating complex, high-value steroidal compounds with modified biological activity.
• Metabolite Standard: Employed in analytical laboratories for method development and calibration in LC-MS or HPLC analyses of biological samples.
• Drug Discovery: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies to develop new therapeutic candidates.

Basic Information

Product Name	3α-Hydroxy-6-Ethyl-7-Keto-5β-Cholan-24-Oic Acid
CAS No.	915038-26-5
Molecular Formula	C₂₆H₄₂O₅
Molecular Weight	434.61 g/mol
Synonyms	6α-Ethylchenodeoxycholic Acid; 6-Ethyl-CDCA; 6α-Ethyl-3α,7α-dihydroxy-5β-cholan-24-oic Acid; 6-Ethylchenodeoxycholic Acid; 3α,7α-Dihydroxy-6α-ethyl-5β-cholan-24-oic Acid; 6α-Ethyl-3α,7α-dihydroxycholanoic Acid; ECDCA; Obeticholic Acid Intermediate
EINECS	Contact for details

Quality Control

Our 3α-Hydroxy-6-Ethyl-7-Keto-5β-Cholan-24-Oic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets exacting standards for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.