Description

R-3,3'-Bis(4-Chlorophenyl)-5,5',6,6',7,7',8,8'-Octahydro-[1,1'-Binaphthalene]-2,2'-Diol is a sophisticated chiral binaphthol derivative, a key structural motif in asymmetric synthesis. This compound matters as a high-value ligand precursor and chiral building block, enabling the precise construction of complex molecules with defined stereochemistry. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional materials.

Application

• Chiral Ligand Synthesis: A crucial precursor for constructing axially chiral phosphine and N-heterocyclic carbene (NHC) ligands used in asymmetric catalysis.
• Pharmaceutical Intermediates: Serves as a sophisticated scaffold in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring high stereochemical purity.
• Asymmetric Catalysis: The binaphthol core can be directly utilized or modified to create catalysts for enantioselective transformations like hydrogenation, cross-coupling, and C-H activation.
• Agrochemical Research: Employed in the development of novel, stereochemically-defined herbicides, fungicides, and plant growth regulators.
• Advanced Material Precursor: Used in the synthesis of chiral polymers, liquid crystals, or metal-organic frameworks (MOFs) with specific optical or electronic properties.
• Academic & Industrial R&D: A valuable tool for chemists exploring new methodologies in stereocontrolled synthesis and organometallic chemistry.

Basic Information

Item	Details
Product Name	R-3,3'-Bis(4-Chlorophenyl)-5,5',6,6',7,7',8,8'-Octahydro-[1,1'-Binaphthalene]-2,2'-Diol
CAS No.	915038-18-5
Molecular Formula	C32H26Cl2O2
Molecular Weight	513.45 g/mol
Synonyms	(R)-3,3'-Bis(4-chlorophenyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthalene-2,2'-diol; (R)-H8-BINOL-3,3'-di(4-chlorophenyl); (R)-Octahydro-3,3'-bis(4-chlorophenyl)-2,2'-dihydroxy-1,1'-binaphthyl; R-3,3'-Di(4-chlorophenyl)-H8-BINOL; (R)-3,3'-Bis(p-chlorophenyl)-5,5',6,6',7,7',8,8'-octahydro-2,2'-dihydroxy-1,1'-binaphthyl; R-3,3'-Bis(4-Cl-Ph)-H8-BINOL
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Quality is verified through comprehensive analytical techniques including HPLC, chiral HPLC, 1H/13C NMR, and mass spectrometry. A detailed Certificate of Analysis (COA), documenting identity, purity, chiral purity, and impurity profile, is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.